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A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome
NCT06872125 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· New York: New York, Rochester
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A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
NCT07227857 ·
Phase: Phase 1, Phase 2 ·
Ages: 2 Years to 12 Years ·
Sex: All (male and female)
· New York: Rochester
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A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
NCT07219407 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· New York: New York
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A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
NCT06422923 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· New York: Syracuse
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A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
NCT06660394 ·
Phase: Phase 3 ·
Ages: 2 Years to 65 Years ·
Sex: All (male and female)
· New York: New York
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A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
NCT05716100 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: Woodmere
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A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
NCT04462770 ·
Phase: Phase 3 ·
Ages: 2 Years and older ·
Sex: All (male and female)
· New York: New York
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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
NCT06132893 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· New York: Amherst, Hawthorne, New York, Stony Brook
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A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
NCT05667142 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· New York: Amherst, Syracuse, Woodmere
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A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
NCT04715646 ·
Phase: Phase 3 ·
Ages: 1 Month and older ·
Sex: All (male and female)
· New York: Hawthorne
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An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
NCT05066217 ·
Phase: Phase 3 ·
Ages: 2 Years to 55 Years ·
Sex: All (male and female)
· New York: New York
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An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures
NCT06908356 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· New York: Middletown
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Biology of Juvenile Myoclonic Epilepsy
NCT03400371 ·
Phase: Not specified ·
Ages: 10 Years to 40 Years ·
Sex: All (male and female)
· New York: New York
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Brain Metabolism Observed at 3 Tesla or 7 Tesla in Health and Metabolic Disease
NCT05085704 ·
Phase: Not specified ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· New York: New York
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Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
NCT07051629 ·
Phase: Phase 1 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· New York: Amherst
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Genetic Developmental and Epileptic Encephalopathy Natural History Study for Clinical Trial Readiness
NCT07413211 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New York: New York
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Hippocampal Oscillations During Exploration
NCT07224191 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· New York: New York
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Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
NCT05219617 ·
Phase: Phase 3 ·
Ages: 4 Years to 55 Years ·
Sex: All (male and female)
· New York: The Bronx
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Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
NCT04419272 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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Modulating Movement Intention Via Cortical Stimulation
NCT03233399 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· New York: New York
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NYU Epilepsy Self-Management Study
NCT07087821 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: Brooklyn, New York
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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New York: New York
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Prediction of Anxiety and Memory State
NCT06551090 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· New York: New York
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Prospective Natural History Study of POLG Disease
NCT07775872 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New York: New York
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Risk Factors for Sudden Unexplained Death in Epilepsy
NCT01662453 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New York: New York
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SLC6A1-NDD Prospective Longitudinal Natural History Study
NCT07531511 ·
Phase: Not specified ·
Ages: Up to 17 Years ·
Sex: All (male and female)
· New York: New York
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STXBP1 and SYNGAP1 Related Disorders Natural History Study
NCT06555965 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· New York: New York
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SeizEAR Safety Study
NCT07088835 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· New York: New York
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Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures
NCT07594119 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· New York: New York
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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
NCT05135091 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· New York: Great Neck, New York, Syracuse
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Telephone-Based Support Programs for People With Epilepsy
NCT05082181 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· New York: New York
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The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy
NCT05019885 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders
NCT04322734 ·
Phase: Not specified ·
Ages: Up to 18 Years ·
Sex: All (male and female)
· New York: Brooklyn