Clinical trials recruiting for Generalized anxiety disorder

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

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Recruiting trials

• A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
  NCT07478744 · Phase: Phase 2 · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)
  NCT07807865 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders
  NCT04793828 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
  NCT07759128 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
  NCT07767903 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 5 locations
• Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study
  NCT06218030 · Phase: Phase 4 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Anxiety Skills Study
  NCT07774481 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Brief Smartphone Treatment Study
  NCT04846777 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
  NCT05467683 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 2 locations
• Clinical Trial of Shugan Jieyu Capsule in Generalized Anxiety Disorder
  NCT05772104 · Phase: Phase 3 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Cohort Study on Medical Students' Mental Health
  NCT07305701 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Continuous Theta Burst Stimulation for Generalized Anxiety Disorder
  NCT07770919 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Electroclinical Correlation of Anxiety
  NCT05393518 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
  NCT04900064 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Group vs. Individual Metacognitive Therapy for Generalized Anxiety Disorder
  NCT07579897 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders
  NCT06661460 · Phase: Not applicable (e.g. observational or device study) · Ages: 8 Years to 17 Years · Sex: All (male and female) · 1 location
• Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)
  NCT04557891 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 3 locations
• Massage for GAD: Neuroimaging and Clinical Correlates of Response
  NCT06506253 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 64 Years · Sex: All (male and female) · 1 location
• Metacognitive Therapy Compared to Cognitive-behavioral Therapy
  NCT07382323 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mindful Self-Compassion for Anxiety Disorders and Depression
  NCT05671419 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method
  NCT07028216 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Navigated cTBS for the Treatment of Generalized Anxiety Disorder
  NCT07121712 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 60 Years · Sex: All (male and female) · 2 locations
• Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
  NCT06563310 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 24 Years · Sex: All (male and female) · 1 location
• Phase 3 Clinical Trial of Buagafuran Capsules in the Treatment of GAD
  NCT06243640 · Phase: Phase 3 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Phase Ⅲ Clinical Trial of Buagafuran Capsules in the Treatment of GAD
  NCT06243614 · Phase: Phase 3 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder
  NCT07330648 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• RCT of Short-Term Psychoanalytic vs. Cognitive Behavioral Therapy for GAD
  NCT06831708 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
  NCT07489651 · Phase: Phase 2 · Ages: 18 Years to 74 Years · Sex: All (male and female) · 28 locations
• Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety
  NCT05427708 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Risk and Resiliency Factors in the RCMP: A Prospective Investigation
  NCT05527509 · Phase: Not applicable (e.g. observational or device study) · Ages: 19 Years to 57 Years · Sex: All (male and female) · 1 location
• Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
  NCT06376734 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 6 locations
• Stepped Versus Stratified Care for Anxiety Disorders in Youth
  NCT06942429 · Phase: Not applicable (e.g. observational or device study) · Ages: 8 Years to 17 Years · Sex: All (male and female) · 1 location
• Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
  NCT06701903 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 51 locations
• Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
  NCT06480383 · Phase: Phase 2 · Ages: No age limits stated · Sex: All (male and female) · 56 locations
• Teletherapy vs. In-Person Cognitive Behavioral Therapy for Generalized Anxiety Disorder
  NCT07119515 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 45 Years · Sex: All (male and female) · 1 location
• Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
  NCT06934525 · Phase: Not applicable (e.g. observational or device study) · Ages: 5 Years to 18 Years · Sex: All (male and female) · 1 location
• The Effectiveness of Transdiagnostic CBT Protocol on Anxiety Disorders
  NCT06422728 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression
  NCT06724666 · Phase: Not applicable (e.g. observational or device study) · Ages: 13 Years to 17 Years · Sex: All (male and female) · 2 locations
• Triage Survey for Psychiatry Research Eligibility
  NCT05800925 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 6 locations
• Trigeminal Nerve Stimulation in Treatment-resistant Generalized Anxiety Disorder: a Feasibility Study
  NCT06278909 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity
  NCT05117255 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Where We All Meet: ACT Approach to Adolescents Anxiety Disorders
  NCT05906849 · Phase: Not applicable (e.g. observational or device study) · Ages: 14 Years to 18 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Generalized anxiety disorder often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Generalized anxiety disorder trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.