Clinical trials recruiting for Obsessive-compulsive disorder

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

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Recruiting trials

• A Multicenter Pediatric Deep Brain Stimulation Registry
  NCT06585618 · Phase: Not specified · Ages: 0 Years to 18 Years · Sex: All (male and female) · 1 location
• A Precision Medicine Approach to Target Engagement for Emotion Regulation
  NCT05651295 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Accelerated Rotational Field Deep TMS for Treating OCD
  NCT07116785 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Accelerated rTMS Therapeutic Approach for Refractory Obsessive-Compulsive Disorder
  NCT07198594 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Accelerated rTMS in Hospitalized Patients With OCD: a Feasibility and Mechanistic Study
  NCT07135414 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• An OCD Prevention Programme for at Risk Adults
  NCT06262464 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Anxiety Skills Study
  NCT07774481 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder
  NCT04934007 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
  NCT04131829 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Brief Culturally Adapted CBT for OCD
  NCT07232823 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
  NCT05609916 · Phase: Not applicable (e.g. observational or device study) · Ages: 7 Years to 17 Years · Sex: All (male and female) · 1 location
• CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy
  NCT05467683 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 2 locations
• Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders
  NCT03918577 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Clinical Outcomes in Pediatric Obsessive-Compulsive Disorder
  NCT01635569 · Phase: Not applicable (e.g. observational or device study) · Ages: 5 Years to 18 Years · Sex: All (male and female) · 1 location
• Concentrated Exposure and Response Prevention for Children With Obsessive-compulsive Disorder
  NCT06621381 · Phase: Not applicable (e.g. observational or device study) · Ages: 6 Years to 12 Years · Sex: All (male and female) · 1 location
• Cortical Stimulation to Treat Obsessive Compulsive Disorder
  NCT04958096 · Phase: Not applicable (e.g. observational or device study) · Ages: 22 Years to 75 Years · Sex: All (male and female) · 1 location
• Deep Brain Stimulation Surgery for the Treatment of Refractory Obsessive-Compulsive Disorder
  NCT05995951 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Deep Brain Stimulation for Obsessive-compulsive Disorder
  NCT06628752 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder
  NCT06660225 · Phase: Not applicable (e.g. observational or device study) · Ages: 22 Years to 75 Years · Sex: All (male and female) · 1 location
• Developing Brain, Impulsivity and Compulsivity
  NCT04631042 · Phase: Not specified · Ages: 6 Years to 80 Years · Sex: All (male and female) · 1 location
• Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period.
  NCT05961306 · Phase: Not specified · Ages: 18 Years and older · Sex: Female · 4 locations
• Digital Mindfulness-Based Therapy for Obsessive-Compulsive Disorder
  NCT07701616 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 65 Years · Sex: All (male and female) · 2 locations
• Effect of Emotion-Focused Acceptance and Commitment Therapy on Obsessive-Compulsive Disorder Symptom Severity
  NCT07622654 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Effect of the French Version If the Metagognitive Bibliotherapy Program "MYMCT" on Obsessive-compulsive Symptoms
  NCT06494735 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Efficacy and Influencing Factors of ALIC-NAc Deep Brain Stimulation in Treatment-Refractory Obsessive-Compulsive Disorder
  NCT07031544 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 10 locations
• Efficacy and Influencing Factors of Deep Transcranial Magnetic Stimulation in the Treatment of OCD
  NCT06692114 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 50 Years · Sex: All (male and female) · 1 location
• Efficacy of Nitrous Oxide in OCD: Pilot Study
  NCT03826693 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• European Study of Quality of Life in Resistant OCD Patients Treated by STN DBS
  NCT02844049 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 69 Years · Sex: All (male and female) · 8 locations
• Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD
  NCT04882839 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Evaluation Study: Obsessive-compulsive Disorders in Childhood and Young Adulthood
  NCT04723485 · Phase: Not specified · Ages: 4 Years to 18 Years · Sex: All (male and female) · 1 location
• Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
  NCT04900064 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
  NCT05940324 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Glucose Consumption During Deep Brain Stimulation With Functional [18F]FDG-Brain-PET in Obsessive-Compulsive Disorder
  NCT05577598 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• ICBT for OCD in Children With Autism
  NCT06582225 · Phase: Not applicable (e.g. observational or device study) · Ages: 7 Years to 17 Years · Sex: All (male and female) · 3 locations
• ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
  NCT05906069 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Identifying Local Field Potential Biomarkers for Obsessive-compulsive Disorder Treatment With Deep Brain Stimulation
  NCT06542224 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 4 locations
• Imagery Rescripting as a Stand-alone Treatment for OCD and BDD.
  NCT06346301 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Improving Obsessive-compulsive Disorder Treatments: from Lesions to Neuromodulation Targets
  NCT06490965 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Individually Targeted Neuromodulation for Contamination-based OCD
  NCT05048251 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Integrating Exposure and Response Prevention and Habit Reversal Techniques to Treat a Tourettic Subtype of Obsessive-Compulsive Disorder (Tourettic OCD)
  NCT07725926 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Interpretation Bias as a Mechanism of Treatment Response in OCD
  NCT05224414 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Ketamine in OCD: Efficacy and Effects on Stress and Cognition
  NCT05577585 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
  NCT05783817 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Mechanisms of Exposure Therapy for OCD
  NCT06173752 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Neural Mechanisms of Obsessive-compulsive Disorder (OCD) Treatment Failure
  NCT05520398 · Phase: Not specified · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Neural Mechanisms of Response Inhibition Training for OCRD
  NCT05377125 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Neurobiological Markers of Treatment Response for Anxiety and OCD
  NCT05663489 · Phase: Not specified · Ages: 16 Years and older · Sex: All (male and female) · 1 location
• Neurostimulation Versus Therapy for Problems With Emotions
  NCT05712057 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Neurosurgical Outcome Network
  NCT06724029 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 27 locations
• Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis
  NCT06754319 · Phase: Not specified · Ages: 7 Years to 17 Years · Sex: All (male and female) · 1 location
• Pharmaco(Epi)Genetic, Proteomic, and Microbiomic Study of Obsessive-Compulsive Disorder
  NCT02431845 · Phase: Not applicable (e.g. observational or device study) · Ages: 19 Years to 70 Years · Sex: All (male and female) · 1 location
• Pharmacogenetics of Antidepressant-Induced Disinhibition
  NCT03953014 · Phase: Not specified · Ages: 6 Years to 17 Years · Sex: All (male and female) · 2 locations
• Physiological Brain Atlas Development
  NCT00575081 · Phase: Not specified · Ages: 6 Years to 90 Years · Sex: All (male and female) · 2 locations
• Pilot Study of RR-HNK in OCD
  NCT06575075 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Pragmatic Trial of Obsessive-compulsive Disorder
  NCT04539951 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Precision Analytic Research Methods in OCD
  NCT07011901 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Project EMPOWER-OCD
  NCT07158801 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.
  NCT07347405 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Reinforcement Learning and Obsessive-compulsive Disorder: Exploring the Role of the Orbitofrontal Cortex
  NCT06566781 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Retrospective Analyses of TrakStar Database
  NCT06917339 · Phase: Not specified · Ages: 5 Years to 120 Years · Sex: All (male and female) · 1 location
• SEEG-Guided DBS for OCD
  NCT05623306 · Phase: Not applicable (e.g. observational or device study) · Ages: 22 Years to 75 Years · Sex: All (male and female) · 2 locations
• SONATA LIFU for OCD
  NCT07728994 · Phase: Phase 2 · Ages: 22 Years to 80 Years · Sex: All (male and female) · 1 location
• Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)
  NCT06611592 · Phase: Phase 2 · Ages: 18 Years to 64 Years · Sex: All (male and female) · 1 location
• Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Treatment Refractory Obsessive Compulsive Disorder (OCD)
  NCT07704632 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 85 Years · Sex: All (male and female) · 1 location
• Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
  NCT06376734 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 6 locations
• Short and Intensive Treatment of Children and Adolescents With Obsessive-Compulsive Disorder
  NCT04730011 · Phase: Not applicable (e.g. observational or device study) · Ages: 8 Years to 18 Years · Sex: All (male and female) · 1 location
• Study of Dextromethorphan in OCD and Related Disorders
  NCT04899687 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Study on Therapeutic Mechanism of Natural Psychotherapy for Neurosis
  NCT06443125 · Phase: Not applicable (e.g. observational or device study) · Ages: 15 Years to 60 Years · Sex: All (male and female) · 2 locations
• TMS + Exposure Therapy for Pediatric OCD
  NCT05931913 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 21 Years · Sex: All (male and female) · 2 locations
• The STEP-MIED Trial: Digital Stepped-Care for Emotional Disorders
  NCT07458100 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Towards Remission and Full Recovery From Obsessive-compulsive Disorder
  NCT06318806 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Transcranial Magnetic Stimulation and Psychotherapy for Treating Obsessive-Compulsive Disorder
  NCT07146438 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
  NCT07065669 · Phase: Not applicable (e.g. observational or device study) · Ages: 13 Years to 17 Years · Sex: All (male and female) · 1 location
• University of Iowa Interventional Psychiatry Service Patient Registry
  NCT04480918 · Phase: Not specified · Ages: 18 Years to 99 Years · Sex: All (male and female) · 2 locations
• Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients
  NCT07245134 · Phase: Not applicable (e.g. observational or device study) · Ages: 17 Years to 55 Years · Sex: All (male and female) · 1 location
• Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: Outpatients Trial
  NCT07206199 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• tDCS Associated With Symptom Provocation in the Management of Patients With Resistant Obsessive Compulsive Disorder
  NCT06017713 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Obsessive-compulsive disorder often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Obsessive-compulsive disorder trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.