Clinical trials recruiting for Overweight
89
Recruiting trials
47
US states with sites
46
Countries
34%
Accept healthy volunteers
Phase breakdown
Drugs and treatments being studied
| Intervention | Trials |
|---|---|
| Eloralintide | 8 |
| NNC0487-0111 | 5 |
| Semaglutide | 5 |
| Cagrilintide | 4 |
| Acetaminophen | 3 |
| Maridebart cafraglutide | 3 |
| Orforglipron | 3 |
| UBT251 | 3 |
| ASC30 tablets A1 | 2 |
| Macupatide | 2 |
| Oral contraceptive | 2 |
| PF-08653944 | 2 |
Where trials are recruiting (top US states)
| State | Recruiting trials |
|---|---|
| California | 34 |
| Texas | 34 |
| Florida | 30 |
| New York | 25 |
| Georgia | 22 |
| South Carolina | 22 |
| North Carolina | 21 |
| Missouri | 20 |
| Illinois | 19 |
| Ohio | 19 |
| Virginia | 19 |
| Arizona | 18 |
Top cities
San Antonio, Texas 22Houston, Texas 21Austin, Texas 16Miami, Florida 16Las Vegas, Nevada 15Morehead City, North Carolina 14Cincinnati, Ohio 13Jacksonville, Florida 13Chicago, Illinois 12Dallas, Texas 12
Self-screener
Recruiting trials
- A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults
- A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
- A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
- A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-5817 Injection
- A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
- A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
- A Research Study Investigating the Effect of NNC0497-0040 in Healthy Participants, Participants With Overweight or Obesity, and Participants With Type 1 Diabetes With Overweight or Obesity
- A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or Obesity
- A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
- A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become Pregnant
- A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight
- A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
- A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
- A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or Obesity
- A Research Study to See How NNC0487-0111 Affects the Body's Energy Use After a Weight Loss in Adults Living With Obesity, Compared to a Low-calorie Diet or Placebo
- A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants
- A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or Obese
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
- A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight
- A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
- A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
- A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
- A Study of Eloralintide (LY3841136) in Participants With Overweight or Obesity
- A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
- A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy
- A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
- A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
- A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
- A Study of SHR-2906 Injection in Healthy Subjects With a Single Dose and in Obese Patients With Multiple Doses
- A Study to Evaluate the Effects of Enicepatide in Participants With Obesity or Overweight, With or Without Type 2 Diabetes
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
- A Study to Investigate the Efficacy and Safety of Elecoglipron in Asian Participants With Obesity or Overweight With or Without Type 2 Diabetes Mellitus
- A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
- A Study to Learn How the Study Medicine Called PF-08653945 is Taken up Into the Blood in Adults With Overweight or Obesity
- A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity
- A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight
- A Trial of Oral VRB-103 Alone or in Combination With Oral Ecnoglutide (VRB-101) in Participants With Obesity or Overweight
- AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
- AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
- AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
- AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
- Avoid and Resist Strategies for Weight Management
- Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study
- Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study
- Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
- Comparing the Efficacy and Safety of the EndoZip System and Apollo ESG in Obese Patients
- Comparison of Genotype-Based Dietary Counseling Versus Standard Dietary Counseling on Weight Loss and Fat Mass Reduction
- Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change
- Dietary Supplementation on Fat Oxidation
- Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
- Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate
- Effect of Partial Dietary Replacement From Animal to Plant-Based Protein for Type 2 Diabetes Management
- Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction Tendencies
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
- Efficacy and Safety of IBI362 in Hypertensive Patients With Overweight/Obesity
- Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
- Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
- Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
- Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
- Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
- Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
- HealthyTogether: RCT of a Dyadic Weight Management Intervention
- IBI3042 Study in Healthy Participants and Overweight or Obese Participants
- Impact of Obesity on Microvascular Insulin Action and Cardiorespiratory Fitness in Type 1 Diabetes
- Impact of Overweight, Obesity, and Lifestyle Changes on Work Performance and Well-Being in Medical Residents
- Impact of Satiating Compounds and Hypocaloric Diet on Weight, Cardiometabolic and Osteoarticular Health in Obesity
- Improving Glycemic Control With Electrical Stimulation
- In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes
- International Weight Control Registry
- Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
- Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women
- Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer
- Optimization of Chrononutrition to Reduce the Risk of Disease in Shift Workers
- Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
- Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
- Semaglutide for Post-Smoking Cessation Weight Management
- Study to Evaluate the Efficacy and Safety of KDS2010 in Overweight or Obese Patients
- Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
- The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.
- The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults
- The PreEclampsia Postpartum Prevention Trial
- Time Restricted Feeding, Muscle, and Metabolism
- Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
- Weight Loss in Adults Using Semaglutide (Real-world Study)
- Weight and Metabolic Management Study
- Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
- Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure
Related conditions
Trials recruiting for Overweight often also study these conditions. Each links to its own recruiting-trial list.
Obesity 1512Type 2 diabetes 891Hypertension 1201Chronic Weight Management 4Oxidative Stress 9Overweight or Obesity 33Overweight and/or Obesity 11Obese 12Microvascular Function 5Low Physical Fitness 3
Common questions
Are these trials free to join?
Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.
How do I know if I am eligible for Overweight trials?
Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.
Is this list complete?
No. For the full list, search ClinicalTrials.gov.