Clinical trials recruiting for Psychosis

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

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Recruiting trials

• A Case Series of Culturally-adapted CBTp for Black People in the UK
  NCT07252206 · Phase: Not applicable (e.g. observational or device study) · Ages: 16 Years and older · Sex: All (male and female) · 1 location
• A Mental Health Services Engagement Program for Racial and Ethnic Minority Young Adults
  NCT06508450 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 34 Years · Sex: All (male and female) · 1 location
• A Novel Blood Test as a Biomarker in Mental Health
  NCT06856161 · Phase: Not specified · Ages: 19 Years and older · Sex: All (male and female) · 3 locations
• A Probiotic Strategy for Antipsychotic-induced Metabolic Dysfunction
  NCT06729671 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
  NCT06947941 · Phase: Phase 3 · Ages: 55 Years to 90 Years · Sex: All (male and female) · 44 locations
• Acceptability, Feasibility and Preliminary Outcomes of the Kiso Mind App for Outpatients With Schizophrenia Spectrum Disorders
  NCT07395206 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
  NCT04789915 · Phase: Phase 1 · Ages: 18 Years to 45 Years · Sex: All (male and female) · 1 location
• Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
  NCT06978452 · Phase: Not specified · Ages: 9 Years to 25 Years · Sex: All (male and female) · 1 location
• Biomarkers in Clozapine-responding Schizophrenia
  NCT05316883 · Phase: Phase 4 · Ages: 18 Years to 64 Years · Sex: All (male and female) · 1 location
• Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis
  NCT07001878 · Phase: Phase 4 · Ages: 18 Years to 25 Years · Sex: All (male and female) · 2 locations
• Cerebellar Modulation of Cognition in Psychosis
  NCT06107764 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 2 locations
• Clozapine-related Immunodeficiency in Parkinsons Disease
  NCT06634641 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cognitive Strategies in Early Psychosis 2
  NCT07263022 · Phase: Phase 3 · Ages: 18 Years to 35 Years · Sex: All (male and female) · 1 location
• Combining mHealth and Nurse-delivered Care to Improve the Outcomes of People With Serious Mental Illness in West Africa
  NCT05703711 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting
  NCT05814913 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Determining the Role of Social Reward Learning in Social Anhedonia
  NCT05617898 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 35 Years · Sex: All (male and female) · 2 locations
• Dundrum Forensic Redevelopment Evaluation Study: D-FOREST Study.
  NCT05074732 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• E-Detection Tool for Emerging Mental Disorders
  NCT05127278 · Phase: Not specified · Ages: 12 Years to 35 Years · Sex: All (male and female) · 2 locations
• Early Psychosis: Investigating Cognition
  NCT07196423 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder
  NCT06197048 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder
  NCT06048172 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Effectiveness of the Combination of Water Aerobics and Metacognitive Training
  NCT05455593 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
  NCT07056894 · Phase: Not applicable (e.g. observational or device study) · Ages: 16 Years to 30 Years · Sex: All (male and female) · 2 locations
• Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis
  NCT05796401 · Phase: Phase 3 · Ages: 15 Years to 30 Years · Sex: All (male and female) · 13 locations
• Enhanced Coordinated Specialty Care for Early Psychosis
  NCT06071858 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 5 locations
• Enhancing Rehabilitation for Veterans With Serious Mental Illness
  NCT06586164 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 83 Years · Sex: All (male and female) · 1 location
• Examining the Effects of Estradiol on Neural and Molecular Response to Reward
  NCT05282277 · Phase: Phase 4 · Ages: 45 Years to 55 Years · Sex: Female · 2 locations
• Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
  NCT03601026 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 21 Years · Sex: All (male and female) · 1 location
• HYEEG Discourse in Psychosis: A Neurobehavioural Study
  NCT06978803 · Phase: Not specified · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Immune Mechanisms of Antipsychotic Treatment Response
  NCT06687694 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Investigating the Effect of a Single-dose of Levetiracetam on Brain Function, Chemistry and Cognitive Performance in Psychosis Risk
  NCT06224530 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 40 Years · Sex: All (male and female) · 1 location
• Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder
  NCT06221852 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 45 Years · Sex: All (male and female) · 1 location
• Mentalization Based Treatment (MBT) in Help Seeking Youths With a Clinical High-Risk Condition for Psychosis (CHR-P)
  NCT07093671 · Phase: Not applicable (e.g. observational or device study) · Ages: 14 Years to 30 Years · Sex: All (male and female) · 1 location
• Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder
  NCT07213492 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 35 Years · Sex: All (male and female) · 1 location
• Multiomic Diagnostics in Youth With Psychosis
  NCT05457140 · Phase: Not applicable (e.g. observational or device study) · Ages: 7 Years to 17 Years · Sex: All (male and female) · 1 location
• Neural Basis of Social Cognition Deficits
  NCT05185128 · Phase: Not applicable (e.g. observational or device study) · Ages: 12 Years to 18 Years · Sex: All (male and female) · 1 location
• Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness
  NCT04940663 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Neuroimmunology Registry and Biobank
  NCT06958341 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 4 locations
• Normobaric Oxygen Therapy for Individuals With First-Episode Psychosis
  NCT04368039 · Phase: Not applicable (e.g. observational or device study) · Ages: 15 Years to 35 Years · Sex: All (male and female) · 1 location
• Outcomes From Remediation and Behavioural Intervention Techniques
  NCT05731414 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients
  NCT05365347 · Phase: Not applicable (e.g. observational or device study) · Ages: 16 Years to 35 Years · Sex: All (male and female) · 1 location
• Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia
  NCT07196462 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Predicting Psychotic Relapse Using Speech-Based Early Detection
  NCT06978894 · Phase: Not specified · Ages: 16 Years and older · Sex: All (male and female) · 3 locations
• Preliminary Efficacy of an mHealth Intervention in West Africa
  NCT07276321 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Real-life Assessment of Brexpiprazole (Rexulti) in Schizophrenia and in Depressive Disorders
  NCT05962216 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Semantic and Syntactic Computerized Analysis of Free Speech
  NCT03525054 · Phase: Not specified · Ages: 15 Years to 30 Years · Sex: All (male and female) · 3 locations
• Stratification and Treatment in Early Psychosis Study - ENHANCE
  NCT06778564 · Phase: Phase 3 · Ages: 16 Years to 40 Years · Sex: All (male and female) · 17 locations
• Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With Psychosis
  NCT06036316 · Phase: Not applicable (e.g. observational or device study) · Ages: 16 Years to 55 Years · Sex: All (male and female) · 1 location
• Study on the Use of Exergames to Support Older Adults With Psychosis
  NCT07060742 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years and older · Sex: All (male and female) · 1 location
• TOPUS - Testing an Implemented Intervention to Reduce Duration of Untreated Psychosis
  NCT07716969 · Phase: Not specified · Ages: 18 Years to 35 Years · Sex: All (male and female) · 2 locations
• Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis
  NCT05440214 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
  NCT05131035 · Phase: Not applicable (e.g. observational or device study) · Ages: 14 Years to 20 Years · Sex: All (male and female) · 1 location
• The Effect of Combined Brain Stimulation and Yoga for Improving Cognitive Function in Psychosis
  NCT07747181 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• The Effectiveness of Individualized Imagery Scripts on Sleep, Psychosis, and Suicidality Among Inpatients With Psychosis
  NCT06194344 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The Mouth Matters in Mental Health Trial -2
  NCT07470437 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 5 locations
• Toward a Computationally-Informed, Personalized Treatment for Hallucinations
  NCT04366518 · Phase: Early Phase 1 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Virtual Reality and Artificial Intelligence in Treatment for Patients With Psychosis
  NCT06728241 · Phase: Not applicable (e.g. observational or device study) · Ages: 17 Years to 65 Years · Sex: All (male and female) · 2 locations

Related conditions

Trials recruiting for Psychosis often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Psychosis trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.