Clinical trials recruiting for Bipolar disorder
212
Recruiting trials
35
US states with sites
41
Countries
20%
Accept healthy volunteers
Phase breakdown
Drugs and treatments being studied
| Intervention | Trials |
|---|---|
| Lithium | 5 |
| KarXT | 3 |
| ABBV-932 | 2 |
| Bupropion | 2 |
| Cannabidiol | 2 |
| Cariprazine | 2 |
| Clozapine | 2 |
| Escitalopram | 2 |
| Ketamine | 2 |
| Ketamine Hydrochloride | 2 |
| Lamotrigine | 2 |
| Lithium Carbonate | 2 |
Where trials are recruiting (top US states)
| State | Recruiting trials |
|---|---|
| Texas | 29 |
| California | 26 |
| Georgia | 21 |
| Florida | 18 |
| New York | 18 |
| Illinois | 17 |
| Massachusetts | 17 |
| Ohio | 16 |
| Arkansas | 15 |
| Maryland | 14 |
| Pennsylvania | 11 |
| Washington | 11 |
Top cities
Atlanta, Georgia 16Houston, Texas 16Chicago, Illinois 12Little Rock, Arkansas 12Miami, Florida 12Cincinnati, Ohio 10Austin, Texas 9Boston, Massachusetts 9Miami Lakes, Florida 9New York, New York 9
Self-screener
Recruiting trials
- A Cohort Study of Disease Prediction Model for High-risk Population With Bipolar Disorder
- A Mental Health Services Engagement Program for Racial and Ethnic Minority Young Adults
- A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness
- A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate
- A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
- A Study of Abilify® Tablet(Aripiprazole) as an Adjunctive Treatment in the Bipolar Depression
- A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
- A Study of Home-use Brain Stimulation to Treat Bipolar Depression
- A Study of Olanzapine in Participants With Bipolar Disorder.
- A Study of the Behavioral Variant of Frontotemporal Dementia and Bipolar Disorder: a Neuroimaging and Epigenetics Integrated Approach
- A Study on the Preference of Risperidone Dosage Forms
- A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
- A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Adult Participants With Bipolar Disorder
- A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
- A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
- A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor
- A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)
- A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder
- ALTO-100 in Bipolar Disorder With Depression (BD-D)
- Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
- Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
- Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study
- Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian
- Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression
- An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania
- An Examination of the Performance of QbMobile in Differential Diagnosis Associated With ADHD Symptoms
- An Exploratory Study on the Prediction of Recurrence Risk of Bipolar Disorder Using Sentiment Analysis Technology Based on Multi-modal Feature Fusion
- An Innovative Master Platform for Clinical Trials in Mood Disorders
- Apathy-related Neurobehavioral Markers of Cognitive Decline in Old-age Bipolar Disorders: Proof-of-concept
- App and Body Fat Scale in the Management of Overweight Patients
- Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
- Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder
- Basal Plasma Lithium Levels and Suicidal Events
- Behavioural Activation for Bipolar Depression
- Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
- BioClock: Bright Light Therapy for Depressive Disorders
- Biocollection on Peripheral Inflammation
- Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental Disorders
- Biomarkers Predictive of Thymic Evolution and Therapeutic Response at 2 Years in Patients With a First Psychotic Episode
- Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
- Bipolar Research And Innovation Network - BRAIN
- Bipolar Resection vs Enucleation of Prostate
- Brexpiprazole Treatment for Bipolar I Depression
- Brief Treatment for Trauma Nightmares in Trauma-exposed Adults With Bipolar Disorder
- CBT-CP for Veterans With SMI
- CLOZAPINE Response in Biotype-1
- COMpassion for Psychiatric Disorders And Self-Stigma
- Cannabidiol for Bipolar Depression (CBD-BD)
- Cerebellar Modulation of Cognition in Psychosis
- Cerebellar Stimulation and Cognitive Control
- Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital
- Characterization of High-Level Cognitive Impairments in Patients With Neuropsychiatric Disorders
- Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
- Children's Bipolar Network Treatment Trial I
- Chinese Longitudinal and Systematic Study of Bioplar Disorder
- Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression
- Cognitive Stimulation for Elderly Bipolar Patients
- Cognitive Strategies in Early Psychosis 2
- Comparison Between Bipolar Transurethral Resection of the Prostate and Moses Assisted Holmium Laser Enucleation of the Prostate
- Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder
- Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
- Creating a Global Research Database That Connects Genetic Information and Long-term Health Data to Improve Personalized Treatment for People With Serious Mental Illness
- Decoding Emotional Dynamics in Bipolar Disorder
- Deep Brain Stimulation of Treatment-Resistant Bipolar Depression
- Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
- Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression
- Development and Application of Precision Treatment Strategies for Common Mental Disorders
- Dialectical Behavior Therapy for Youth With and/or at Familial Risk for Bipolar Disorder
- EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
- Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression
- Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psychosis or Bipolar Affective Disorder
- Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study
- Effectiveness of a Pragmatic, Metabolic Care Clinic for Patients With Severe Mental Illness - The Meta Care Clinic
- Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
- Effects of Schizophrenia and Bipolar Disorder on Exercise Capacity, Pulmonary Function, and Quality of Life
- Efficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression
- Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders
- Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
- Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression
- Ejaculation-Preserving Versus Standard Bipolar TUEP for BPH
- Electrosurgical Bipolar Systems Versus Conventional Electrocautery After SLNBx
- Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome
- Enhanced Coordinated Specialty Care for Early Psychosis
- Enhancing Rehabilitation for Veterans With Serious Mental Illness
- Enhancing Veteran-Clinical Collaboration in VA PRRCs
- Epigenetic Enhancement of Cognitive Training in Aging Mood Disorder Populations
- Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
- Evaluation of Efficiency of One Day Patient/Caregiver Psychoeducation on the Caregiver's Burden
- Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
- Evaluation of the Efficacy, Safety, and Tolerability of Lacosamide in Major Depressive Episodes of Bipolar Disorder Types I and II.
- Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic Aspects
- Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder (BD)
- Exercise Therapy in Mental Disorders-study
- Exercise and Olanzapine-samidorphan
- Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
- FOCUS Bipolar: Families Opening Conversations for Understanding Signs
- Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression
- Feasibility and Preliminary Results of the Efficacy of Blue-Blocking Glasses on Manic Symptoms in Bipolar Disorder
Related conditions
Trials recruiting for Bipolar disorder often also study these conditions. Each links to its own recruiting-trial list.
Depression 1463Schizophrenia 386Bipolar Disorder (BD) 22Bipolar Depression 22Major depressive disorder 166Bipolar I Disorder 17Anxiety 1237Schizoaffective Disorder 31Psychosis 57Depression Bipolar 9
Common questions
Are these trials free to join?
Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.
How do I know if I am eligible for Bipolar disorder trials?
Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.
Is this list complete?
No. For the full list, search ClinicalTrials.gov.