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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
NCT07351058 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Pembroke Pines, Port Orange, St. Petersburg
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A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
NCT07667803 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Plantation, Tampa
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A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers
NCT07159282 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hollywood
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A Phase 1, Multiple Ascending Dose Study to Evaluate HMS1005 in Participants With Type 2 Diabetes
NCT07568678 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Miami
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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
NCT07662044 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville, Orlando
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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Fleming Island, Lauderdale Lakes, Leesburg, Miami Lakes
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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
NCT07664553 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: DeLand, Doral, Ocoee
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A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
NCT07662109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Lake City, Lakeland
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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
NCT06112418 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Cross City, Hialeah, Jacksonville
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A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
NCT07061574 ·
Phase: Phase 1, Phase 2 ·
Ages: 9 Years to 20 Years ·
Sex: All (male and female)
· Florida: Gainesville, Miami
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A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Fleming Island, Hollywood, Saint Augustine, Winter Haven
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A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
NCT07415954 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Hollywood, Miami, Miramar, Ocoee
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A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
NCT07668388 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Hollywood, Miramar, Weston
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A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
NCT07564414 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Fleming Island, Jacksonville, Miami
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A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
NCT07282613 ·
Phase: Phase 3 ·
Ages: 10 Years to 18 Years ·
Sex: All (male and female)
· Florida: Boynton Beach, Jacksonville, Kissimmee, Tamarac
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A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
NCT04786262 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Miami
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A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
NCT07654374 ·
Phase: Phase 3 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· Florida: Clearwater, Fort Myers, Jacksonville, Leesburg
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A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
NCT07340320 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Melbourne, Tampa, Winter Park
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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
NCT06739122 ·
Phase: Phase 3 ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· Florida: Jacksonville, Miami, Orlando, Tamarac
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A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
NCT07282600 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Daytona Beach, Delray Beach, Fleming Island, Inverness
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A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
NCT07321886 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Atlantis, Miami, Mt. Dora, Pembroke Pines
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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
NCT07392190 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Atlantis, Doral, Fleming Island, Jacksonville
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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
NCT06897475 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Ocala, Oviedo
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A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
NCT07215559 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Sunrise
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A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
NCT07743450 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Daytona Beach, Jacksonville, Leesburg
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A Study to Assess the Efficacy, Safety and Tolerability of AT673 Co-administered With Semaglutide in Adult Participants With Type 2 Diabetes (T2D) and Overweight or Obesity
NCT07724340 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hollywood, Tampa
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A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
NCT07776509 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Fleming Island, Jacksonville
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A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
NCT07784725 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Jacksonville
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A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
NCT07219602 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville, Lake City, Miami Lakes
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A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
NCT05824975 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville
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A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
NCT07662213 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Crystal River, Hollywood, Jacksonville, Lake City
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A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies
NCT07606066 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville, Lake City, Leesburg, Ocoee
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A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
NCT07589608 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami, Miami Lakes, New Port Richey, Orlando
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A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
NCT07595549 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Crystal River, Lecanto, Miramar, New Port Richey
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A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
NCT07754461 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Fleming Island, Fort Myers, Hollywood
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A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
NCT07590193 ·
Phase: Phase 1 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Aventura
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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07533175 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Fleming Island, Jacksonville, Orlando, Oviedo
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AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
NCT07797335 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Crystal River, Delray Beach, Hollywood
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Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis
NCT06993454 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 55 Years ·
Sex: All (male and female)
· Florida: Orlando
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DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
NCT06525259 ·
Phase: Not specified ·
Ages: 8 Years to 15 Years ·
Sex: All (male and female)
· Florida: St. Petersburg
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Clearwater, Cutler Bay, DeLand
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Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus
NCT07282743 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hialeah Gardens, Lakeland, Miami, Orlando
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Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
NCT07521475 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Tampa, West Palm Beach
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Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
NCT07684144 ·
Phase: Phase 3 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Florida: Miami, Miami Lakes, Orlando, Weston
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GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
NCT07228117 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 7 Years to 85 Years ·
Sex: All (male and female)
· Florida: Tampa, West Palm Beach
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HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
NCT07546929 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Doral, Edgewater, Fort Myers, Miami
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Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
NCT06906640 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: St. Petersburg
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Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
NCT06906627 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: St. Petersburg
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Low-Dose Pioglitazone in Patients With NASH (AIM 2)
NCT04501406 ·
Phase: Phase 2 ·
Ages: 21 Years to 75 Years ·
Sex: All (male and female)
· Florida: Gainesville
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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892 ·
Phase: Phase 4 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Florida: Miami, Pembroke Pines
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PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
NCT06567795 ·
Phase: Not specified ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Florida: West Palm Beach
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Pancreatic Islet Transplantation Into the Anterior Chamber of the Eye
NCT02846571 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Miami
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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
NCT07502508 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Florida: Fort Myers, Miami Lakes, Winter Park
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Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets
NCT07502495 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Fort Myers, Miami Lakes, Winter Park
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Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
NCT07216391 ·
Phase: Phase 2 ·
Ages: 4 Years to 34 Years ·
Sex: All (male and female)
· Florida: Gainesville
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RESET System Pivotal Trial (Rev F)
NCT04101669 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 65 Years ·
Sex: All (male and female)
· Florida: Miami
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Registry for Stage 2 Type 1 Diabetes
NCT06481904 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Florida: Gainesville, Jacksonville, Miami, Tampa
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Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
NCT06681428 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami
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Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D
NCT07399678 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Florida: Miami
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Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
NCT05267626 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami
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Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
NCT06562907 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Florida: Miami
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Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
NCT07271186 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Doral, Hialeah, Hollywood, Margate
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Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
NCT07527650 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: DeLand, Orlando, The Villages
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Study to Evaluate if Exposure to Drug is Impacted in Participants With Renal Insufficiency
NCT07385547 ·
Phase: Phase 1 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Miami, Miami Lakes, Orlando
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The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
NCT03761446 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years to 80 Years ·
Sex: All (male and female)
· Florida: Orlando
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Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
NCT07296484 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Edgewater, Fort Lauderdale, Miami, New Port Richey
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WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
NCT06861790 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 20 Years to 75 Years ·
Sex: All (male and female)
· Florida: Gainesville
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Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity
NCT07554443 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville