-
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
NCT07351045 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Bellaire, Brownsville, Corpus Christi, Dallas
-
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
NCT07351058 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Brownsville, Dallas, Edinburg, Houston
-
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
NCT07667803 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston, Humble, Irving
-
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
NCT07662044 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Fort Worth, Irving
-
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
NCT07662135 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: San Antonio
-
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
NCT07664553 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston, Round Rock, San Antonio
-
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
NCT07662109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, McKinney, Paris, San Antonio
-
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
NCT06112418 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Texas: Abilene, Beaumont, Greenville, Houston
-
A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes
NCT07061574 ·
Phase: Phase 1, Phase 2 ·
Ages: 9 Years to 20 Years ·
Sex: All (male and female)
· Texas: Houston
-
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: El Paso, San Antonio
-
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
NCT07415954 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Dallas, Houston, Shavano Park
-
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
NCT07668388 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Austin, Houston, Lampasas, San Antonio
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A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
NCT07564414 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Amarillo, Austin, Dallas, Euless
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A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
NCT07282613 ·
Phase: Phase 3 ·
Ages: 10 Years to 18 Years ·
Sex: All (male and female)
· Texas: Houston, Shavano Park
-
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
NCT04786262 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Texas: Dallas
-
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
NCT07654374 ·
Phase: Phase 3 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· Texas: Austin, Farmers Branch, Houston, San Antonio
-
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
NCT07340320 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Dallas, Mesquite, San Antonio, Stephenville
-
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
NCT06739122 ·
Phase: Phase 3 ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· Texas: Dallas, Houston
-
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
NCT07282600 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Corpus Christi, Dallas, Fort Worth
-
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
NCT07321886 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Bellaire, Dallas, San Antonio
-
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
NCT07392190 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston, Kingwood, Mission
-
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
NCT06897475 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Houston, Mesquite, Round Rock, Shavano Park
-
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
NCT07215559 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Dallas, Houston, Richmond, Shavano Park
-
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
NCT07743450 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Brownsville, DeSoto, Frisco
-
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
NCT07776509 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
-
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
NCT07784725 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston, San Antonio, Sugar Land, Waco
-
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
NCT07219602 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston, San Antonio
-
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
NCT07662213 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston, Katy, San Antonio
-
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
NCT07024823 ·
Phase: Phase 1 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
NCT07589608 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Austin, Dallas, Houston, San Antonio
-
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
NCT07595549 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston, San Antonio
-
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
NCT07754461 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Brownsville, Conroe, Dallas
-
ACT Intervention for Type 2 Diabetes Management for Rural and Underserved Community
NCT06028503 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Conroe
-
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07533175 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston
-
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
NCT07797335 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Texas: Amarillo, Austin, Conroe, Corpus Christi
-
Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
NCT06108076 ·
Phase: Early Phase 1 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents
NCT06943001 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 16 Years ·
Sex: All (male and female)
· Texas: Houston
-
Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions
NCT05168605 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Texas: Dallas
-
Balance Control and Recovery in Diabetes Peripheral Neuropathy
NCT06544876 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 99 Years ·
Sex: All (male and female)
· Texas: Austin
-
Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
NCT06959277 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· Texas: Galveston
-
CGM for Management of Type 2 Diabetes in Pregnancy
NCT06628453 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 50 Years ·
Sex: Female
· Texas: Houston
-
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
NCT05142189 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
-
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
NCT06246799 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
DISCOVERY of Risk Factors for Type 2 Diabetes in Youth
NCT06525259 ·
Phase: Not specified ·
Ages: 8 Years to 15 Years ·
Sex: All (male and female)
· Texas: Houston
-
Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
NCT05950282 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
-
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Brownsville, Dallas, El Paso
-
Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System
NCT07579702 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 14 Years to 75 Years ·
Sex: All (male and female)
· Texas: Houston
-
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
NCT06810726 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Corpus Christi
-
Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
NCT07521475 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Austin, McKinney, San Antonio
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Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
NCT07684144 ·
Phase: Phase 3 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Texas: Austin, Bellaire, Corpus Christi, Denison
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Feasibility and Adherence to a Technology-assisted Home-based Strength Training Program in Adults With Type 2 Diabetes Mellitus and Mild Cognitive Impairment
NCT07416799 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years to 80 Years ·
Sex: All (male and female)
· Texas: Galveston
-
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
NCT07228117 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 7 Years to 85 Years ·
Sex: All (male and female)
· Texas: Austin, Denton, McKinney
-
Gastroparesis Registry 4
NCT05846802 ·
Phase: Not specified ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Texas: El Paso
-
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
NCT06706284 ·
Phase: Phase 4 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
NCT07546929 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Irving, Lewisville, McKinney
-
Heat and Exercise in Aging as Therapy (HEAT)
NCT06580964 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· Texas: Lubbock
-
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
NCT06906640 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston, Temple
-
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
NCT06906627 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Temple
-
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
NCT06451757 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
-
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
NCT07780188 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 11 Years to 17 Years ·
Sex: Female
· Texas: College Station
-
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
NCT06593327 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: No age limits stated ·
Sex: All (male and female)
· Texas: Dallas
-
PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents
NCT06959901 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 12 Years to 18 Years ·
Sex: All (male and female)
· Texas: Houston
-
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
NCT05390892 ·
Phase: Phase 4 ·
Ages: 40 Years to 80 Years ·
Sex: All (male and female)
· Texas: Katy, McKinney
-
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
NCT07502508 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Texas: Austin, Dallas, Houston, Lewisville
-
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets
NCT07502495 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Austin, Dallas, Houston, Lewisville
-
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
NCT05838287 ·
Phase: Phase 4 ·
Ages: 30 Years to 70 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
Polypill for Prevention of Cardiomyopathy
NCT06143566 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Texas: Dallas
-
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
NCT02969798 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
Quantifying Hepatic Mitochondrial Fluxes in Humans
NCT05305287 ·
Phase: Phase 4 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
RESET System Pivotal Trial (Rev F)
NCT04101669 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 65 Years ·
Sex: All (male and female)
· Texas: Houston
-
ROME GS System Study
NCT07518004 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: San Antonio
-
Registry for Stage 2 Type 1 Diabetes
NCT06481904 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Texas: Austin, Dallas, Fort Worth, Houston
-
SALUD-M: Acceptance Based Coping Skills for Hispanic/Latinx Military Patients With Type 2 Diabetes
NCT07674628 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
SGLT2i, Hepatic Glucose Production, and SNS
NCT07053293 ·
Phase: Early Phase 1 ·
Ages: 30 Years to 75 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia
NCT07053306 ·
Phase: Phase 1 ·
Ages: 30 Years to 75 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
SGLT2i, Pioglitazone, and Ketone Production in T2D
NCT07053319 ·
Phase: Phase 1 ·
Ages: 30 Years to 75 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
SGLTi, Hepatic Glucose Production and Ketogenesis
NCT05960656 ·
Phase: Phase 1 ·
Ages: 30 Years to 75 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes
NCT07599982 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Austin
-
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
NCT05267626 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Houston, San Antonio
-
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
NCT06562907 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· Texas: San Antonio
-
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
NCT07271186 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Arlington, Dallas, DeSoto, El Paso
-
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
NCT07296484 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Austin, Dallas, Houston, Lampasas
-
Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes
NCT06593314 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: No age limits stated ·
Sex: All (male and female)
· Texas: Dallas