Phase 3 Hypertension trials recruiting now

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Other phases for Hypertension

Phase 3 Hypertension trials

• A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
  NCT07218029 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 135 locations
• A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study
  NCT07661329 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 16 locations
• A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
  NCT07285655 · Phase: Phase 3 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 36 locations
• A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier)
  NCT07816185 · Phase: Phase 3 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 3 locations
• A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
  NCT06742723 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 771 locations
• A Randomized, Double-blind, Multi-center, Active-controlled, Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of THP-00101, THP-00102, and THP-00103 in Subjects With T2DM and Essential Hypertension
  NCT06647745 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 2 locations
• A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease
  NCT07223502 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
  NCT05179876 · Phase: Phase 3 · Ages: 2 Years and older · Sex: All (male and female) · 45 locations
• A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)
  NCT06150560 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
  NCT06822738 · Phase: Phase 3 · Ages: 45 Years and older · Sex: All (male and female) · 27 locations
• A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B
  NCT06441630 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
  NCT07481981 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 20 locations
• APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia
  NCT06408181 · Phase: Phase 3 · Ages: 18 Years to 45 Years · Sex: Female · 1 location
• An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
  NCT07365332 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 43 locations
• An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
  NCT07234032 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 9 locations
• Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology
  NCT05625724 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 21 locations
• Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
  NCT05401357 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 9 locations
• COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities
  NCT07245680 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cardiovascular Protection After Preeclampsia With Enalapril
  NCT07222852 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 1 location
• Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding
  NCT04499898 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy
  NCT04356326 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 20 locations
• Clarifying the Optimal Application of SLT Therapy Trial
  NCT04967989 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 29 locations
• Clinical Trial to Evaluate the Efficacy and Safety of Monotherapy Group of HL1113R1 or HL1113R2 Versus HL1113 (Fixed Dose Combination) in Patients With Essential Hypertension and Type II Diabetes Mellitus
  NCT07552389 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis
  NCT05473520 · Phase: Phase 3 · Ages: 21 Years and older · Sex: All (male and female) · 6 locations
• EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
  NCT07064473 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1147 locations
• EVE TRIAL , ALMA SYSTAM
  NCT06646653 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 2 locations
• Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome
  NCT05726916 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPH
  NCT05140525 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
  NCT07179380 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 145 locations
• Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
  NCT07335211 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Efficacy and Safety of IBI362 in Hypertensive Patients With Overweight/Obesity
  NCT07469800 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma
  NCT05710198 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Evaluate the Efficacy and Safety of Co-administration of JW0104+C2402 in Patients With Hypertension and Dyslipidemia
  NCT06643130 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
  NCT07218783 · Phase: Phase 3 · Ages: 22 Years and older · Sex: All (male and female) · 1 location
• Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
  NCT07218796 · Phase: Phase 3 · Ages: 22 Years and older · Sex: All (male and female) · 1 location
• Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging
  NCT07613099 · Phase: Phase 3 · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Induced Hypertension in Acute PRogrESsive Perforating Artery Stroke Using Peripheral Dilute noREpinephrine
  NCT06059144 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease
  NCT05732727 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 40 locations
• Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
  NCT07080229 · Phase: Phase 3 · Ages: 65 Years and older · Sex: All (male and female) · 1 location
• Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH
  NCT06350032 · Phase: Phase 3 · Ages: Up to 18 Years · Sex: All (male and female) · 5 locations
• LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
  NCT07288398 · Phase: Phase 3 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 282 locations
• Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial
  NCT05405868 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 10 locations
• Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal
  NCT05470205 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
  NCT06274801 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 120 locations
• PAH Exercise Study
  NCT06941441 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia
  NCT06033131 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 17 locations
• PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
  NCT04971720 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Patient-driven Management of BP in CKD
  NCT05546099 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Phase 3 Trial to Evaluate the Efficacy and Safety of CKD-202A
  NCT06643819 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 1 location
• Phase III Study of HRS-7535 for Hypertension With Overweight or Obesity
  NCT07528027 · Phase: Phase 3 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 4 locations
• Pilocarpine Use After Kahook Goniotomy
  NCT03933631 · Phase: Phase 3 · Ages: 30 Years to 100 Years · Sex: All (male and female) · 2 locations
• Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART)
  NCT06922240 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• SGLT2 Inhibition for Cardiovascular Endpoint Reduction in Hypertension
  NCT06804161 · Phase: Phase 3 · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
  NCT05551104 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 1 location
• Safety & Efficacy of Qurs e Fishar in Mild to Moderate Hypertensive Patients in Pakistan
  NCT06852079 · Phase: Phase 3 · Ages: 30 Years to 60 Years · Sex: All (male and female) · 1 location
• Safety and Efficacy of FETO in CDH Phase III
  NCT07187206 · Phase: Phase 3 · Ages: 18 Years to 50 Years · Sex: Female · 1 location
• Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
  NCT07462260 · Phase: Phase 2, Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Stent Implantation Versus Medical Therapy for Idiopathic IntracraniaL Hypertension (SIMPLE)
  NCT05707442 · Phase: Phase 3 · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
  NCT05844462 · Phase: Phase 3 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 1 location
• The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension
  NCT07824674 · Phase: Phase 2, Phase 3 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia
  NCT05287321 · Phase: Phase 3 · Ages: 19 Years to 50 Years · Sex: Female · 1 location
• The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
  NCT06494878 · Phase: Phase 3 · Ages: 18 Years and older · Sex: Female · 12 locations
• The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
  NCT07008365 · Phase: Phase 3 · Ages: 18 Years to 100 Years · Sex: All (male and female) · 4 locations
• Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer
  NCT05460416 · Phase: Phase 3 · Ages: 18 Years to 43 Years · Sex: Female · 1 location
• Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAH
  NCT04062565 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
  NCT07495852 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
  NCT07181109 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1105 locations
• [KJ-TFC-005] Phase 3 Study, Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
  NCT07662759 · Phase: Phase 3 · Ages: 19 Years and older · Sex: All (male and female) · 1 location

Common questions

What does Phase 3 mean?

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Is this list complete?

No. For the full record, search ClinicalTrials.gov.