Clinical trials recruiting for Cognitive Dysfunction

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
  NCT07589595 · Phase: Phase 2 · Ages: 55 Years to 85 Years · Sex: All (male and female) · 72 locations
• ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
  NCT07392723 · Phase: Phase 2 · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
  NCT06733714 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• COMPuter-assisted Self-training to Improve EXecutive Function
  NCT04229056 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 100 Years · Sex: All (male and female) · 2 locations
• China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)
  NCT06650969 · Phase: Not specified · Ages: 45 Years and older · Sex: All (male and female) · 1 location
• Cognitive Effects of Hesperidin in Overweight/Obese Older Adults
  NCT07750223 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 75 Years · Sex: All (male and female) · 1 location
• Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
  NCT05014399 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cognitive Leisure and Preclinical Alzheimer's Disease: Exploring Neural Mechanisms
  NCT06215274 · Phase: Not specified · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits
  NCT06728774 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation
  NCT06936397 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Cognitive Remediation in Forensic Mental Health Care
  NCT04610697 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• Effectiveness of TeleVR App in Cognitive Decline and MCI Patients
  NCT06793735 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)
  NCT07087951 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• HOBSCOTCH-MS-Efficacy Trial
  NCT06951919 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 75 Years · Sex: All (male and female) · 1 location
• High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
  NCT05965518 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Investigating the Neural Correlates of Cognitive Function in Psychosis Patients and Non-Psychiatric Controls With Cannabis Use
  NCT05445180 · Phase: Not applicable (e.g. observational or device study) · Ages: 16 Years to 80 Years · Sex: All (male and female) · 1 location
• Microbiota Mediated Flavonoid Metabolites for Cognitive Health
  NCT07226674 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
  NCT05245903 · Phase: Not specified · Ages: 18 Years to 89 Years · Sex: All (male and female) · 1 location
• Polyphenols and Cognitive Decline
  NCT06507254 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Precision Medicine in the Depression Treatment
  NCT05616559 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Fibromyalgia
  NCT06948903 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Remotely Supervised Computerized Cognitive Stimulation to Reduce Post-chemotherapy Cognitive Difficulties in Patients Treated for Localized Breast Cancer
  NCT06027632 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Months and older · Sex: Female · 25 locations
• Sexual Dysfunction in Women With Multiple Sclerosis (MS)
  NCT07193823 · Phase: Not specified · Ages: 25 Years to 50 Years · Sex: Female · 1 location
• Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
  NCT05565833 · Phase: Phase 2 · Ages: 65 Years and older · Sex: All (male and female) · 1 location
• Stem Cell Therapy for Early Alzheimer's Disease
  NCT06775964 · Phase: Phase 1, Phase 2 · Ages: 60 Years to 80 Years · Sex: All (male and female) · 1 location
• Study on Aging and Cognitive Impairment in China
  NCT06679296 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Surviving Daily Life
  NCT07054723 · Phase: Not specified · Ages: 40 Years and older · Sex: Female · 1 location
• Tennessee Alzheimer's Project
  NCT05372172 · Phase: Not specified · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• The Application of an AI-driven Multimodal Predictive Model for Cognitive Impairment in Patients With Type 2 Diabetes Mellitus
  NCT07128186 · Phase: Not specified · Ages: 40 Years to 75 Years · Sex: All (male and female) · 21 locations
• Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
  NCT05649800 · Phase: Not specified · Ages: 65 Years and older · Sex: All (male and female) · 2 locations
• Vortioxetine for Cognitive Function in ALK-positive NSCLC Treated With Lorlatinib
  NCT07633626 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• bWell-D Pilot Randomized Controlled Trial
  NCT06546917 · Phase: Not applicable (e.g. observational or device study) · Ages: 19 Years to 55 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Cognitive Dysfunction often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Cognitive Dysfunction trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.