Clinical trials recruiting for Cognitive Impairment

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

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Recruiting trials

• A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
  NCT06411561 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China
  NCT05886114 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years to 80 Years · Sex: All (male and female) · 1 location
• A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
  NCT05081596 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses
  NCT05877196 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years and older · Sex: All (male and female) · 1 location
• Amygdala Memory Enhancement
  NCT05065450 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Biomarker Exploration in Aging, Cognition and Neurodegeneration
  NCT03860857 · Phase: Phase 3 · Ages: 60 Years and older · Sex: All (male and female) · 1 location
• Blood Tests for Alzheimer's Disease: Can Plasma Biomarkers Diagnose and Predict Disease Progression
  NCT07717567 · Phase: Not specified · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• Brain Health in Breast Cancer Survivors
  NCT04297020 · Phase: Not specified · Ages: 35 Years to 65 Years · Sex: Female · 1 location
• Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy
  NCT07193277 · Phase: Phase 4 · Ages: 60 Years to 85 Years · Sex: All (male and female) · 1 location
• COgnitioN With VERiciGuat Evaluation in Heart Failure
  NCT06601465 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Cerebral Protection in Transcatheter Left Atrial Appendage Occlusion
  NCT05369195 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 6 locations
• Characteristics of Papez Loop Neural Network in T2DM （Type 2 Diabetes Mellitus）
  NCT06912321 · Phase: Not specified · Ages: 45 Years to 70 Years · Sex: All (male and female) · 1 location
• Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers
  NCT06417086 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease
  NCT03810794 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 85 Years · Sex: All (male and female) · 3 locations
• Cognitive Impairment in Ageing People
  NCT04360200 · Phase: Not specified · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
  NCT05014399 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cognitive Remediation Intervention to Prepare for Transition of Care
  NCT05336201 · Phase: Phase 2 · Ages: 10 Years to 18 Years · Sex: All (male and female) · 1 location
• Cognitive Screening and Multidomain Intervention Targeting Cognitive Decline in Type 2 Diabetes (The Brain Care Study)
  NCT07250789 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years and older · Sex: All (male and female) · 3 locations
• Cognitive Stimulation for Elderly Bipolar Patients
  NCT04184375 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years and older · Sex: All (male and female) · 1 location
• Community-based Screening for Alzheimer's Disease
  NCT07570719 · Phase: Not specified · Ages: 60 Years to 80 Years · Sex: All (male and female) · 4 locations
• Develop a Novel Occupational Training Program for Schizophrenia Patients Based on Virtual Reality Techniques
  NCT05830903 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 40 Years · Sex: All (male and female) · 1 location
• Diagnostic Evaluation of Dementia with Lewy Bodies Using a Multimodal Approach
  NCT06068361 · Phase: Not specified · Ages: 55 Years to 85 Years · Sex: All (male and female) · 1 location
• Early Age-Related Hearing Loss Investigation (EARHLI)
  NCT06174038 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 75 Years · Sex: All (male and female) · 1 location
• Effect and Mechanism of Brain Stimulation for Parkinson's Disease With Cognitive Impairment
  NCT06090682 · Phase: Not specified · Ages: Up to 75 Years · Sex: All (male and female) · 1 location
• Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV
  NCT06013579 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 3 locations
• Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression
  NCT07610655 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Efficacy and Safety of Canagliflozin in the Treatment of Type 2 Diabetes With Mild Cognitive Impairment
  NCT07711171 · Phase: Phase 4 · Ages: 40 Years to 75 Years · Sex: All (male and female) · 1 location
• Efficacy of Bright Light Therapy on Cognitive Impairment in Major Depressive Disorder and Its Neuroimaging Mechanisms: Protocol for a Randomised Controlled Trial
  NCT07508215 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 60 Years · Sex: All (male and female) · 2 locations
• Epigenetic Enhancement of Cognitive Training in Aging Mood Disorder Populations
  NCT07404085 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 75 Years · Sex: All (male and female) · 1 location
• Evaluating the Efficacy of the Pain Identification and Communication Toolkit
  NCT06168604 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression
  NCT04935619 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 55 Years · Sex: All (male and female) · 1 location
• HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
  NCT06930560 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years to 100 Years · Sex: All (male and female) · 1 location
• Hjernegym - Effects of Exergaming in Psychosis: a Clinical Intervention Study
  NCT05858255 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Impact of Anodal tDCS and Virtual Reality on Cognitive Dysfunction in Patients With Multiple Sclerosis
  NCT07114809 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 3 locations
• Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study
  NCT07146412 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years to 75 Years · Sex: All (male and female) · 1 location
• Improving Self-Care of Caregivers of Adults in Homecare With Heart Failure and Cognitive Impairment
  NCT07220798 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 101 Years · Sex: All (male and female) · 1 location
• Investigating Dynamic Interactions in Distributed Cognitive Control Networks
  NCT05927974 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
  NCT04855825 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention
  NCT06986096 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years to 80 Years · Sex: All (male and female) · 1 location
• Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
  NCT07042087 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years to 80 Years · Sex: All (male and female) · 1 location
• MODAFIMS: A Trial to Evaluate Predictors of Response to MODAFinil in Patients With Multiple Sclerosis
  NCT06592352 · Phase: Phase 2 · Ages: 18 Years to 64 Years · Sex: All (male and female) · 1 location
• Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
  NCT06727773 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Female · 1 location
• Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease
  NCT07226219 · Phase: Phase 1 · Ages: 8 Years to 17 Years · Sex: All (male and female) · 1 location
• MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction
  NCT06191965 · Phase: Phase 2, Phase 3 · Ages: 18 Years to 35 Years · Sex: All (male and female) · 3 locations
• Multimodal Assesment of Alzheimer Patients
  NCT06448403 · Phase: Not specified · Ages: 65 Years and older · Sex: All (male and female) · 1 location
• Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
  NCT06596746 · Phase: Not specified · Ages: 10 Years and older · Sex: All (male and female) · 2 locations
• Neurologic Stem Cell Treatment Study
  NCT02795052 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 6 locations
• Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS
  NCT06589544 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 100 Years · Sex: All (male and female) · 2 locations
• Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
  NCT05245903 · Phase: Not specified · Ages: 18 Years to 89 Years · Sex: All (male and female) · 1 location
• RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
  NCT06553235 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 1 location
• Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden
  NCT06757569 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Shanghai At Risk for Alzheimer's Disease: a Cohort Study
  NCT05597410 · Phase: Not specified · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• Study of ALTO-101 in Patients With Schizophrenia
  NCT06502964 · Phase: Phase 2 · Ages: 21 Years to 55 Years · Sex: All (male and female) · 14 locations
• TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure
  NCT05250349 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Technological Balance and Gait Rehabilitation in Patients With Multiple Sclerosis.
  NCT05983809 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
  NCT05885295 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Theta Deep Brain Stimulation for Cognitive Enhancement in Parkinson's Disease
  NCT06518824 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Visual Frailty in Ageing
  NCT06604104 · Phase: Not specified · Ages: 60 Years and older · Sex: All (male and female) · 2 locations
• intErnet-based iNterventions FOR Cardiac arrEst suRvivors
  NCT06395558 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 2 locations

Related conditions

Trials recruiting for Cognitive Impairment often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Cognitive Impairment trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.