Clinical trials recruiting for Parkinson's disease

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• "Self-Compassion and Self-Efficacy in Parkinson's Disease: Associations With Symptoms, Function, and Quality of Life"
  NCT07488351 · Phase: Not specified · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• "Turkish Validity and Reliability of the Heat Sensitivity Scale for Individuals With Parkinson's Disease"
  NCT07710625 · Phase: Not specified · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• 10,000 Step Club: Community Walking Program for People with Parkinson's Disease
  NCT06605183 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years to 85 Years · Sex: All (male and female) · 1 location
• 24-months Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor
  NCT06570421 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• 40 Hz Flickering for Insomnia in Parkinson's Disease
  NCT07323121 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 75 Years · Sex: All (male and female) · 1 location
• 7.0T Magnetic Resonance Imaging Study of Parkinson's Disease
  NCT06449404 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• A Clinical Study to Evaluate the Safety of MF1, a New Treatment for Parkinson's Disease-related Disorders (MF1 Study)
  NCT07666022 · Phase: Phase 1 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 1 location
• A Clinical Study to Evaluate the Safety, and Tolerability of BBM-P002 in the Treatment of Parkinson's Disease
  NCT07195825 · Phase: Phase 1 · Ages: 40 Years to 70 Years · Sex: All (male and female) · 1 location
• A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
  NCT06565195 · Phase: Phase 1 · Ages: 30 Years to 80 Years · Sex: All (male and female) · 16 locations
• A Clinical Trial of Parkinson's Disease Treatment by HiPSCs Derived Dopaminergic Neural Precursor Cells
  NCT06145711 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years to 70 Years · Sex: All (male and female) · 2 locations
• A Comparative Performance Study Between High and Standard Resolution Positron Emission Tomography Camera Using [18F] AV-133 in Prodromal Parkinson's Disease
  NCT07809438 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Comprehensive, Multimodal Characterization of Prodromal PD in Subjects With RBD
  NCT07790744 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's
  NCT04664634 · Phase: Phase 3 · Ages: 22 Years and older · Sex: All (male and female) · 1 location
• A Long-Term Follow-up Study of the Severe Parkinson's Disease Patients Administered the IPS101A Gene Therapy Product.
  NCT07629115 · Phase: Not specified · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease
  NCT06753331 · Phase: Phase 1, Phase 2 · Ages: 40 Years to 72 Years · Sex: All (male and female) · 2 locations
• A Novel Accessible and Widespread Healthcare Service Model Based on Technology Innovation for Objective (Early) Diagnosis and Therapeutic Monitoring of Parkinson's Disease Promoting Continuity of Care
  NCT06907589 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 5 locations
• A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease
  NCT07705373 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 3 locations
• A Novel Robotic System for Motor-cognitive Exercise for Patients With Parkinson's Disease
  NCT06730074 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 75 Years · Sex: All (male and female) · 1 location
• A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
  NCT06680830 · Phase: Phase 2 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 72 locations
• A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease
  NCT07322887 · Phase: Phase 2 · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• A Phase I Study in Healthy Volunteers and Parkinson's Disease (PD) Patients.
  NCT07630545 · Phase: Phase 1 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 18 locations
• A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease
  NCT07170475 · Phase: Phase 1 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease
  NCT07543861 · Phase: Phase 1 · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications
  NCT05539196 · Phase: Not specified · Ages: 30 Years to 99 Years · Sex: All (male and female) · 5 locations
• A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
  NCT04991831 · Phase: Not specified · Ages: 30 Years to 99 Years · Sex: All (male and female) · 8 locations
• A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
  NCT06304285 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 70 Years · Sex: All (male and female) · 1 location
• A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
  NCT06285643 · Phase: Phase 2 · Ages: 45 Years to 75 Years · Sex: All (male and female) · 46 locations
• A Study of Buntanetap in Participants With PD
  NCT07284784 · Phase: Phase 2, Phase 3 · Ages: 40 Years to 85 Years · Sex: All (male and female) · 27 locations
• A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
  NCT06765668 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 27 locations
• A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
  NCT06809400 · Phase: Phase 1 · Ages: 30 Years to 85 Years · Sex: All (male and female) · 14 locations
• A Study to Assess Change in Disease Symptoms in Adult Participants With Advanced Parkinson Disease Using Subcutaneous Foslevodopa/Foscarbidopa in Belgium
  NCT07382440 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 12 locations
• A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa
  NCT07284342 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 16 locations
• A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
  NCT06976268 · Phase: Phase 2, Phase 3 · Ages: 40 Years to 80 Years · Sex: All (male and female) · 22 locations
• A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery
  NCT06683378 · Phase: Phase 1 · Ages: 45 Years to 75 Years · Sex: All (male and female) · 1 location
• A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSA
  NCT07604116 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
  NCT07432958 · Phase: Phase 2 · Ages: 30 Years to 80 Years · Sex: All (male and female) · 30 locations
• A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
  NCT07174310 · Phase: Phase 3 · Ages: 50 Years to 85 Years · Sex: All (male and female) · 192 locations
• A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
  NCT07804615 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 30 locations
• A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
  NCT06944522 · Phase: Phase 3 · Ages: 45 Years to 75 Years · Sex: All (male and female) · 43 locations
• A Trial of Lu AF28996 in Participants With Parkinson's Disease (PD)
  NCT07513441 · Phase: Phase 1 · Ages: 35 Years to 85 Years · Sex: All (male and female) · 4 locations
• A Trial to Evaluate the Safety, Tolerability and Preliminary Efficacy of NCR201 in the Treatment of Subjects With Parkinson's Disease
  NCT06978920 · Phase: Phase 1 · Ages: 40 Years to 75 Years · Sex: All (male and female) · 1 location
• A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease
  NCT07157735 · Phase: Phase 2 · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LBT-3627 in Healthy Participants and in Participants With Parkinson's Disease.
  NCT06466525 · Phase: Phase 1 · Ages: 30 Years to 89 Years · Sex: All (male and female) · 2 locations
• A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
  NCT07330258 · Phase: Not specified · Ages: 45 Years to 75 Years · Sex: All (male and female) · 27 locations
• AR Gait Training for Parkinson's Disease
  NCT06598878 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years and older · Sex: All (male and female) · 1 location
• AV133 Longitudinal Imaging Study in Patients With Early and Prdromal Parkinson's Disease
  NCT06456684 · Phase: Not specified · Ages: 30 Years and older · Sex: All (male and female) · 1 location
• Accelerated TMS for Freezing of Gait in Parkinson's Disease
  NCT06982638 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• Accelerated Temporal Interference Stimulation on Bilateral Subthalamic Nucleus for Parkinson's Disease and Secondary Parkinson's Syndrome
  NCT07568067 · Phase: Not applicable (e.g. observational or device study) · Ages: Up to 85 Years · Sex: All (male and female) · 1 location
• Accelerated rTMS for Apathy in Parkinson's Disease
  NCT07399496 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 85 Years · Sex: All (male and female) · 1 location
• Acceptability of the Somnomat Casa for the Treatment of Parkinson's Disease
  NCT06386497 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 85 Years · Sex: All (male and female) · 2 locations
• Action Observation and Motor Imagery Therapy in Parkinson's Disease
  NCT06154356 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's Disease
  NCT06874803 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years to 80 Years · Sex: All (male and female) · 1 location
• Adapting rHIRE and Sleep Monitoring in Parkinson's Disease
  NCT07498296 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) China Study
  NCT07216976 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 5 locations
• Adaptive DBS for PD
  NCT07635823 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 9 locations
• Adaptive DBS to Offset STN Dysregulation During Exercise in PD
  NCT06296810 · Phase: Not specified · Ages: 20 Years to 70 Years · Sex: All (male and female) · 1 location
• Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)
  NCT05070013 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 2 locations
• Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease
  NCT06909045 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Aim 3 Particle Swarm Optimization PIGD
  NCT05934747 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 85 Years · Sex: All (male and female) · 1 location
• An Exploratory Study to Confirm Efficacy of Modified Deep Cervical Lymphovenous Anastomosis (LVA) in Alzheimer's Disease/ Parkinson's Disease
  NCT06852352 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 2 locations
• An Online Physical Activity Coaching Intervention for People With PD in Qatar
  NCT06962930 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• An Unblinded, Single Arm, Pilot Observational Study to Test the Safety, Tolerability, Immunogenicity and the Biological Effects of TRB-001 Vaccination.
  NCT07777484 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease
  NCT07428447 · Phase: Not specified · Ages: 50 Years to 85 Years · Sex: All (male and female) · 4 locations
• Application of Thoracic Epidural SCS for Managing FOG in Patients With Advanced Parkinson's Disease
  NCT06630702 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• Artificial Intelligence in Molecular Imaging: Predicting Parkinson's Risk in REM Sleep Behavior Disorder
  NCT06629207 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Artificial Intelligence-assisted MDS-UPDRS Assessment for Parkinson's Disease
  NCT07381751 · Phase: Not specified · Ages: 18 Years to 95 Years · Sex: All (male and female) · 2 locations
• Association of VAgus Nerve Stimulation and Treadmill Training for GAit Rehabilitation in DE Novo Parkinson's Disease
  NCT07337226 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• At-home taVNS for Neurorehabilitation in Parkinson's Disease
  NCT07536022 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• Attention and Eye Movement in Parkinson's Disease
  NCT06899022 · Phase: Not applicable (e.g. observational or device study) · Ages: 19 Years to 90 Years · Sex: All (male and female) · 1 location
• Auditory Sleep Stimulation or Sham in People With Parkinson Disease Mild Cognitive Impairment During Cognitive Training
  NCT07441915 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Autoimmune Features of Neurodegenerative Disorders
  NCT04239079 · Phase: Not specified · Ages: 55 Years to 90 Years · Sex: All (male and female) · 2 locations
• Automated Daytime Adaptive Deep Brain Stimulation Parameter Optimization in Patients Implanted With Percept Neurostimulator
  NCT07682311 · Phase: Not applicable (e.g. observational or device study) · Ages: 25 Years to 75 Years · Sex: All (male and female) · 1 location
• BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease
  NCT07138560 · Phase: Phase 4 · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• Balance Confidence and Kinesiophobia in Parkinson's Disease
  NCT06751797 · Phase: Not specified · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• Balance Tele-Rehab in Parkinson's Disease
  NCT05680597 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 85 Years · Sex: All (male and female) · 1 location
• Bilateral Subthalamic Stimulation in PD Patients With Impulse Control Disorders - STIMPulseControl
  NCT06498349 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 12 locations
• Biofluid Research on Age-Related or Inherited Neurodegeneration
  NCT07798700 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Biological Determinants and Neural Compensation of Dysphagia in Parkinson's Disease
  NCT07299448 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Biomechanical Effects of EMST® on Swallowing Function in Parkinson's Disease
  NCT07606547 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
  NCT06719583 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 12 locations
• Blood Flow Restriction for Optimizing Balance in Parkinson's Disease
  NCT06508801 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 85 Years · Sex: All (male and female) · 1 location
• Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease
  NCT06588920 · Phase: Not specified · Ages: 40 Years to 80 Years · Sex: All (male and female) · 2 locations
• Brain Mechanisms of Social Perception in Parkinson's Disease
  NCT06884722 · Phase: Not applicable (e.g. observational or device study) · Ages: 30 Years to 75 Years · Sex: All (male and female) · 1 location
• Brain Training to Improve Balance in Parkinson's Disease
  NCT05986643 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Brief Title: Aerobic Training on Cerebrovascular Function, Cognition and Gait in Parkinson's Disease
  NCT07478146 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: All (male and female) · 1 location
• COMPuter-assisted Self-training to Improve EXecutive Function
  NCT04229056 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 100 Years · Sex: All (male and female) · 2 locations
• Caregiver Burden in Parkinson's Disease
  NCT06892717 · Phase: Not specified · Ages: 40 Years to 80 Years · Sex: All (male and female) · 1 location
• Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor
  NCT06993571 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Cerebro Spinal Fluid Collection (CSF)
  NCT04844060 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 2 locations
• Changes in Movement, Fitness, and Quality of Life in People With Parkinson's Disease After Different Exercise Programs
  NCT07221266 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: All (male and female) · 2 locations
• Characterization and Validation of the Short Physical Performance Battery in Individuals Diagnosed With Parkinson's Disease
  NCT07780461 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Characterizing the Pathophysiological Role of the Pallido-thalamocortical Motor Pathway in Parkinson's Disease.
  NCT06692920 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 75 Years · Sex: All (male and female) · 1 location
• Chinese DENOVO PD Registry
  NCT05767151 · Phase: Not specified · Ages: 30 Years to 75 Years · Sex: All (male and female) · 1 location
• Chinese EOPD Registry
  NCT03508960 · Phase: Not specified · Ages: Up to 50 Years · Sex: All (male and female) · 1 location
• Chinese FPD Registry
  NCT03508986 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Chinese PD Registry
  NCT03887663 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Chinese PD-GBA Registry
  NCT03523065 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Chinese PD-LRRK2 Registry
  NCT03523104 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Chinese PD-SNCA Registry
  NCT03523052 · Phase: Not specified · Ages: No age limits stated · Sex: All (male and female) · 1 location
• Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst
  NCT05658302 · Phase: Not specified · Ages: 21 Years and older · Sex: Female · 1 location

Related conditions

Trials recruiting for Parkinson's disease often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Parkinson's disease trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.